Impact of schizophrenia-risk gene dysbindin 1 on brain activation in bilateral middle frontal gyrus during a working memory task in healthy individuals
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چکیده
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متن کاملImpact of cross-disorder polygenic risk on frontal brain activation with specific effect of schizophrenia risk
Evidence suggests that there is shared genetic aetiology across the major psychiatric disorders conferred by additive effects of many common variants. Measuring their joint effects on brain function may identify common neural risk mechanisms. We investigated the effects of a cross-disorder polygenic risk score (PGRS), based on additive effects of genetic susceptibility to the five major psychia...
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ژورنال
عنوان ژورنال: Human Brain Mapping
سال: 2009
ISSN: 1065-9471,1097-0193
DOI: 10.1002/hbm.20862